Healthcare Professional
The information in this section is intended exclusively for HCPs in Europe.
By checking the box you confirm you are a licensed HCP and understand that cenobamate is not approved in Europe.
Welcome to Arvelle’s Medical Information Services
Our mission is to provide you with accurate, timely, tailor-based, balanced scientific information to answer your medical information requests. You can also use this webpage to report any adverse event or product complaint.
To report an adverse event or a product quality complaint, or for medical information, please call:
France +33 (0)1 8824 7098
Germany +49 (0)89 1208 5269
Italy +39 (0)8 0019 4695
Spain +34 (0)9 0903 0223
Sweden +46 (0)8 4468 8842
United Kingdom +44 (0)20 7458 4107
International Free Number 00 800 0825 0827
You can submit medical information requests via email, using medinfo@arvelletx.com
FOS are more often uncontrolled compared to patients with generalised seizures.5 Even with significant therapy advancements, overall treatment outcomes have not significantly improved in the past 20 years.1, 6 Many patients with drug-resistant FOS do not reach seizure freedom, despite trying two or more ASMs.1
Is it any wonder that treatment goals are often reassessed?
* Experiencing at least one seizure in the past five years compared with those who were seizure free for five years.7
** Incidence rate ratio 9.3–13.4.8
Uncontrolled seizures have additional psychosocial implications.
Patients with uncontrolled seizures are:7
- 2x as likely to experience stigma in their daily lives.
- 4.5x more likely to be prevented from driving.
- 3x more likely to have restrictions in employment.
- 2x as likely to have limited education.
In clinical trials, a 50% reduction in seizure frequency is an important endpoint to evaluate efficacy.11 In clinical practice, it is seizure freedom that brings hope back to patients and allows them to have a better life.9
Assess your treatment goals. As your patients persevere, so do you.
-
What is the path to achieving seizure freedom?*
-
What is the most effective way to reduce seizure frequency?
-
How can we reduce seizure severity?**
-
How can we minimise side effects?
* Defined as being free from seizures for 12 months or longer.1
** Defined as seizure type.
The treatment goal in epilepsy therapy should be the reduction of seizure frequency and severity and, eventually, achieving seizure freedom.9, 10, 11